产品货号：
Z24192
中文名称：
PPP1R15B抗体
英文名称：
Anti-PPP1R15B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PPP1R15B Antibody |
| 指标别名 | CREP,PPP1R15B |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,ICC/IF,FCM(Intracellular),Direct ELISA |
| 基因名称 | PPP1R15B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human PPP1R15B recombinant protein (Position:Q211-D657). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PPP1R15B(Protein phosphatase 1,regulatory subunit 15b),also called CREP,promotes dephosphorylation of the transcription initiation factor EIF2-alpha through recruitment of protein phosphatase-1(PP1) catalytic subunits.The PPP1R15B gene is mapped to chromosome 1q32.1 based on an alignment of thePPP1R15B sequence by Hartz(2010).Harding et al.(2009) obtained Ppp1r15b -/- mice at a mendelian ratio.However,Ppp1r15b -/- newborns were half the size of their wildtype littermates,were notably pale,and failed to nurse,and none survived the first day of postnatal life.Ppp1r15b -/- embryos that were also homozygous for an Eif2-alpha mutation that prevented Eif2-alpha phosphorylation were normalized,including elevated birth size and restored red blood cell count,compared with Ppp1r15b -/- embryos with wildtype Eif2-alpha. |
| Uniprot ID | Q5SWA1 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for ICC. |
| 基因名全称 | protein phosphatase 1 regulatory subunit 15B |
| 蛋白名全称 | Protein phosphatase 1 regulatory subunit 15B |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow Cytometry(Intracellular) 1～3μg/1×106 cells Direct ELISA 1:100～1000 |
| Gene ID | 84919 |
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